Creatine Supplementation: Muscular and Cognitive Enhancements
- Kyle LaChance
- Aug 30, 2023
- 2 min read
Updated: Jan 1, 2024

Creatine, a popular workout supplement, plays a pivotal role in producing energy during high-intensity, short-duration activities. While its muscular benefits have been well-documented, emerging research is also pointing towards its cognitive benefits. This blog post delves into the science behind creatine supplementation and its dual benefits for both muscle and mind.
Muscular Benefits of Creatine Supplementation:
Increased Muscle Mass
Creatine supplementation has been consistently linked with increases in muscle mass. This is partly due to an increase in water content within the muscle cell, but also because creatine can promote protein synthesis. Research confirms this by showing that creatine supplementation combined with resistance training led to greater increases in muscle mass compared to resistance training alone.
Enhanced Exercise Performance
Creatine helps replenish ATP (adenosine triphosphate), the body's primary energy molecule, making it especially beneficial for high-intensity, short-duration activities like sprinting or lifting weights. Studies consistently demonstrate that adding creatine to your supplements can improve your performance during short-duration, high-intensity exercise.
Improved Recovery
Creatine can also help reduce muscle cell damage and inflammation following intense exercise, leading to quicker recovery.
Cognitive Benefits of Creatine Supplementation:
Brain Energy Boost
Just as creatine aids in muscle energy production, it also appears to benefit the brain. The brain is an energy-intensive organ, and creatine can help ensure that it has an adequate energy supply, especially during tasks that require intense mental effort. Research published in 2018 discusses evidence demonstrating creatine supplementation led to improved short-term memory and intelligence/reasoning of the participants.
Protection Against Neurological Diseases
Some research suggests that creatine might offer neuroprotective benefits. Since creatine contains antioxidant properties, it can reduce mental fatigue, and improve certain elements of neurological disorders, making it a candidate for fending off neurodegenerative diseases like Parkinson's, Huntington's, and ALS.
Enhanced Cognitive Performance Under Sleep Deprivation
Creatine has shown potential in mitigating the cognitive decline seen after sleep deprivation. One study demonstrated that individuals who took creatine after 24 hours of sleep deprivation showed reduced change in performance and mood compared to those who did not take take the supplement.
Safety and Dosage
It's important to note that while creatine supplementation is generally safe for most people, it's crucial to consult with a healthcare provider before starting. Typical dosing strategies involve a loading phase of around 20 grams per day for 5-7 days, followed by a maintenance phase of 3-5 grams per day. However, a loading phase is not necessary to reach muscular saturation.
Learn More
Creatine, once commonly only known as just an athlete's supplement, is revealing its multifaceted benefits, from muscle growth to cognitive enhancement. As the body of research grows, creatine's position as a potent supplement for both physical and mental health is becoming increasingly evident.
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